HEPATITIS B VIRUS SUPPRESSES COMPLEMENT C9 SYNTHESIS BY LIMITING THE AVAILABILITY OF TRANSCRIPTION FACTOR USF-1 AND INHIBITS FORMATION OF MEMBRANE ATTACK COMPLEX: IMPLICATIONS IN DISEASE PATHOGENESIS

Hepatitis B virus suppresses complement C9 synthesis by limiting the availability of transcription factor USF-1 and inhibits formation of membrane attack complex: implications in disease pathogenesis

Abstract Background The complement system functions primarily as a first-line host defense against invading microbes, including viruses.However, the interaction of Hepatitis B virus (HBV) with the complement-components during chronic HBV infection remains largely unknown.We investigated the mechanism by which HBV inhibits the formation of cytolytic

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MIMU/Odometer Fusion with State Constraints for Vehicle Positioning during BeiDou Signal Outage: Testing and Results

With the rapid development of autonomous vehicles, the demand for reliable positioning results is urgent.Currently, the ground vehicles heavily depend on the Global Navigation Satellite System (GNSS) and the Inertial Navigation System (INS) providing reliable and continuous navigation solutions.In dense urban areas, especially narrow streets with t

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